Description

5,7,8,15-Tetrahydro-2,3-Dimethoxy-6-Methylbenzo[E][1,3]Dioxolo[4,5-K][3]Benzazecin-14(6H)-One is a complex heterocyclic organic compound with the CAS number 528-67-6, serving as a key advanced intermediate in pharmaceutical research and development. Its intricate benzazecine-dioxolo fused ring structure makes it a valuable scaffold for synthesizing novel bioactive molecules targeting the central nervous system. This high-purity compound is essential for medicinal chemists and research institutions focused on developing new therapeutic agents, particularly in the fields of neurology and pharmacology.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel alkaloid-derived pharmaceuticals and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore new bioactive compounds.
• Neurological Drug Discovery: Serves as a precursor in the development of compounds targeting neurological receptors and pathways.
• Academic & Institutional R&D: Employed in university and contract research organization (CRO) laboratories for advanced organic synthesis projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in related compound analysis.
• Chemical Biology Probes: Acts as a starting material for creating specialized probes to study biological mechanisms at the molecular level.

Basic Information

Product Name	5,7,8,15-Tetrahydro-2,3-Dimethoxy-6-Methylbenzo[E][1,3]Dioxolo[4,5-K][3]Benzazecin-14(6H)-One
CAS No.	528-67-6
Molecular Formula	C22H23NO5
Molecular Weight	381.42 g/mol
Synonyms	Benzo[e][1,3]dioxolo[4,5-k][3]benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-2,3-dimethoxy-6-methyl-; 2,3-Dimethoxy-6-methyl-5,7,8,15-tetrahydrobenzo[e][1,3]dioxolo[4,5-k][3]benzazecin-14(6H)-one; NSC 169865; Tetrahydro-2,3-dimethoxy-6-methylbenzo[e][1,3]dioxolo[4,5-k][3]benzazecin-14(6H)-one; 528-67-6; 6-Methyl-2,3-dimethoxy-5,7,8,15-tetrahydrobenzo[e][1,3]dioxolo[4,5-k][3]benzazecin-14(6H)-one
EINECS	Contact for details

Quality Control

Our 5,7,8,15-Tetrahydro-2,3-Dimethoxy-6-Methylbenzo[E][1,3]Dioxolo[4,5-K][3]Benzazecin-14(6H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We are committed to meeting the exacting standards required for pharmaceutical R&D intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.