Description

S-(Hydrogen Malonyl)Coenzyme A is a crucial biochemical intermediate in the malonyl-CoA pathway, serving as a key building block for fatty acid and polyketide biosynthesis. Its high purity and stability are essential for ensuring the accuracy and reproducibility of enzymatic research and metabolic studies. This compound is primarily required by researchers and manufacturers in the fields of biochemistry, pharmaceutical development, and metabolic engineering.

Application

• Enzymology Research: Critical substrate for studying fatty acid synthase (FAS), polyketide synthases (PKS), and other acyltransferase enzymes.
• Metabolic Pathway Analysis: Used in in vitro assays to investigate and map fatty acid synthesis and elongation cycles.
• Pharmaceutical Development: Serves as a precursor in the biosynthesis of complex natural products and potential drug candidates.
• Biocatalyst & Fermentation Studies: Employed to optimize microbial production platforms for biofuels and specialty chemicals.
• Diagnostic Reagent Manufacturing: A component in enzymatic test kits for clinical and research diagnostics related to metabolic disorders.
• Academic & Institutional Research: Fundamental reagent for graduate-level and post-doctoral research in biochemistry and molecular biology.

Basic Information

Item	Detail
Product Name	S-(Hydrogen Malonyl)Coenzyme A
CAS No.	524-14-1
Molecular Formula	C24H40N7O19P3S
Molecular Weight	867.58 g/mol
Synonyms	Malonyl-CoA; Malonyl Coenzyme A; S-Malonylcoenzyme A; Coenzyme A, S-(hydrogen malonyl)-; Malonyl CoA; 3'-Phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3-oxopropanoyl)sulfanyl]ethyl}amino)propyl]amino}butyl} dihydrogen diphosphate)
EINECS	208-354-1

Quality Control

Our S-(Hydrogen Malonyl)Coenzyme A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods, to ensure it meets the exacting standards required for sensitive biochemical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic and light-sensitive nature, the product should be allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	≥ 90% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.