Description

Yohimban is a complex organic alkaloid and a key structural framework found in several bioactive natural products. This compound is of significant interest in pharmaceutical research and development due to its role as the core scaffold for yohimbine and related indole alkaloids. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly those focused on neurological and cardiovascular agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of yohimbine and its derivatives, which are investigated for various therapeutic applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for the identification and quantification of yohimban-based alkaloids.
• Biochemical Research: Employed in pharmacological studies to understand the structure-activity relationships (SAR) of indole alkaloids and their interaction with biological targets.
• Fine Chemical Synthesis: Acts as a specialized building block for the synthesis of novel chemical entities in medicinal chemistry and drug discovery programs.

Basic Information

Product Name	Yohimban
CAS No.	523-06-8
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Yohimbane; 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester; (16α,17α)-16-Carbomethoxy-17-hydroxyyohimban; 3β,17β,20β-Yohimban-16β-carboxylic acid methyl ester; Corynanthan; Aporphine analog
EINECS	208-337-8

Quality Control

Our Yohimban is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and spectroscopic profiles (IR, NMR). A detailed Certificate of Analysis (COA) is supplied with each batch, confirming identity, purity, and conformity to client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.