Description

Allo-Yohimbine is a stereoisomer of the well-known alkaloid yohimbine, distinguished by its specific three-dimensional molecular configuration. This compound is of significant interest in pharmaceutical research and development due to its potential as a reference standard and a key intermediate in the synthesis of specialized bioactive molecules. It serves critical roles for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-characterized chemical entities for analytical and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods like HPLC and LC-MS for quality control and research.
• Biochemical Research: Employed in pharmacological studies to investigate adrenergic receptor interactions and related physiological pathways.
• Fine Chemical Synthesis: Acts as a crucial chiral building block or intermediate in the synthesis of complex natural products and potential drug candidates.
• Analytical Method Development: Serves as a model compound for developing and validating chromatographic separation techniques for alkaloid analysis.
• Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry and neuropharmacology.

Basic Information

Product Name	Allo-Yohimbine
CAS No.	522-94-1
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Alloyohimbine; (16α,17α)-17-Hydroxyyohimban-16-carboxylic acid methyl ester; 3α,17α-Yohimban-16β-carboxylic acid, methyl ester; 16α-Hydroxyyohimban-16β-carboxylic acid methyl ester; Isoyohimbine (ambiguous); α-Yohimbine (ambiguous); Rauwolscine isomer
EINECS	208-327-6

Quality Control

Our Allo-Yohimbine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced chromatographic methods. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.