Description

Lochnerine is a naturally occurring alkaloid compound of significant interest in advanced chemical synthesis and research. This specialized intermediate is valued for its unique structural framework, which serves as a versatile building block for the development of novel compounds. It is primarily utilized by research institutions and pharmaceutical development teams engaged in medicinal chemistry, natural product synthesis, and pharmacological studies.

Application

• Pharmaceutical Research & Development: A key intermediate in the synthesis of novel therapeutic agents and for structure-activity relationship (SAR) studies.
• Medicinal Chemistry: Used as a scaffold or precursor for designing and synthesizing new chemical entities with potential biological activity.
• Natural Product Synthesis: Serves as a critical building block in the total or semi-synthesis of complex indole alkaloids and related natural products.
• Biochemical Research: Employed as a reference standard or probe in biochemical assays to study enzyme interactions or cellular pathways.
• Academic & Institutional Research: Utilized in university and laboratory settings for chemical education and advanced organic synthesis projects.
• Fine Chemical Production: Acts as a specialized intermediate in the custom synthesis of high-value, low-volume fine chemicals for various industrial applications.

Basic Information

Product Name	Lochnerine
CAS No.	522-47-4
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Lochnerine; (19S)-19-Ethyl-19-hydroxy-1,11-dimethoxy-18-oxayohimban-16-carboxylic acid methyl ester; Vincamedine; 16-Carbomethoxy-19-ethyl-19-hydroxy-1,11-dimethoxy-18-oxayohimbane; 18-Oxayohimbine derivative
EINECS	Contact for details

Quality Control

Our Lochnerine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.