Description

Heliotridine is a pyrrolizidine alkaloid, a class of natural products with significant biological activity. This compound serves as a crucial reference standard and research chemical for analytical and pharmacological studies. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and academic research institutions investigating natural product chemistry and toxicology.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of pyrrolizidine alkaloids in drug substances, herbal materials, and finished products.
• Toxicological Research: Serves as a key analyte in studies investigating the hepatotoxic and carcinogenic effects of pyrrolizidine alkaloids.
• Analytical Method Development: Employed as a certified standard for calibrating instruments and validating HPLC, LC-MS, and GC-MS methods.
• Natural Product Isolation & Identification: Acts as a benchmark for the isolation and structural elucidation of related alkaloids in plants from the Boraginaceae, Asteraceae, and Fabaceae families.
• Food & Feed Safety Testing: Critical for monitoring and controlling pyrrolizidine alkaloid contamination in honey, herbal teas, dietary supplements, and animal feed.
• Biochemical Pathway Studies: Used in research to understand the biosynthesis and metabolic pathways of pyrrolizidine alkaloids.

Basic Information

Product Name	Heliotridine
CAS No.	520-63-8
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	Heliotridane-7α-ol; 7α-Hydroxy-1-methylenepyrrolizidine; (1R,7aR)-1,2,3,5,6,7a-Hexahydro-1-hydroxy-3-methylene-7H-pyrrolizin-7-one; Retronecine; 3-Methylene-1-hydroxypyrrolizidine; 1-Hydroxy-2,3-dehydropyrrolizidine; Necine base
EINECS	Contact for details

Quality Control

Our Heliotridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, identity confirmation (IR, MS), and residual solvent analysis, to ensure it meets the stringent requirements for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.