Description

Penniclavine is a naturally occurring ergot alkaloid, a complex indole derivative with significant biological activity. This compound is of high interest for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, medicinal chemistry, and the synthesis of novel therapeutic agents. Our supply ensures high purity and batch-to-batch consistency critical for precise experimental and developmental work.

Application

• Pharmaceutical Reference Standard: Serves as a critical analytical standard for quality control and method validation in the production of ergot-derived pharmaceuticals.
• Medicinal Chemistry Research: Used as a sophisticated building block or lead compound in the discovery and synthesis of new drugs targeting neurological pathways.
• Biochemical Studies: Employed in in-vitro and in-vivo research to study the mechanisms of action of ergot alkaloids and their interactions with neurotransmitter receptors.
• Academic Research: A valuable tool for universities and research institutes conducting studies in pharmacology, toxicology, and natural product chemistry.
• Process Development: Acts as an intermediate in the development and scaling of synthetic routes for complex alkaloids.

Basic Information

Product Name	Penniclavine
CAS No.	519-13-1
Molecular Formula	C16H18N2O
Molecular Weight	254.33 g/mol
Synonyms	Penniclavin; 6-Methyl-9,10-didehydroergoline-8-methanol; (8S)-9,10-Didehydro-6-methyl-8-ergolinemethanol; 8-Hydroxymethyl-6-methyl-9-ergolene; 8-(Hydroxymethyl)-6-methylergoline-9-ene
EINECS	Contact for details

Quality Control

Our Penniclavine is produced and handled under strict quality management protocols to ensure the highest standards of purity and identity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, impurity profile, and identification. We are committed to supplying material suitable for research and development purposes, with specifications that can meet the rigorous demands of analytical and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.