Description

Setoclavine is a naturally occurring ergot alkaloid, a class of compounds known for their complex chemical structures and significant biological activity. This compound serves as a crucial intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on neuroscience, drug discovery, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of ergot alkaloids in research and quality control laboratories.
• Biochemical Research: Acts as a key intermediate or tool compound in studies investigating neurological pathways and receptor interactions.
• Drug Discovery & Development: Serves as a building block or a lead compound for the synthesis of novel molecules with potential therapeutic applications.
• Academic Research: Employed in university and institutional labs for pharmacological studies and chemical synthesis projects.
• Analytical Chemistry: Used as a calibration standard in advanced chromatographic (HPLC, LC-MS) and spectroscopic methods.

Basic Information

Product Name	Setoclavine
CAS No.	519-12-0
Molecular Formula	C₁₆H₁₈N₂O
Molecular Weight	254.33 g/mol
Synonyms	Setoclavine; 6-Methyl-8β-ergolene-8-carboxylic acid, 8,9-didehydro-; 8,9-Didehydro-6-methylergoline-8-carboxylic acid; (6aR,9R,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid; Ergot alkaloid Setoclavine
EINECS	Contact for details

Quality Control

Our Setoclavine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support its use in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.