Description

Corybulbine is a naturally occurring isoquinoline alkaloid with the CAS registry number 518-77-4. This compound is valued for its unique chemical structure, which serves as a critical intermediate and reference standard in advanced research and development. It is primarily sought after by the pharmaceutical, biotechnology, and academic research sectors for applications in medicinal chemistry, neuroscience studies, and as a building block for novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel bioactive molecules and potential drug candidates targeting neurological pathways.
• Reference Standard: For use in analytical laboratories for method development, validation, and quality control of related alkaloid-based products.
• Medicinal Chemistry Studies: To investigate structure-activity relationships (SAR) and for biological screening in pharmacological assays.
• Neuroscience Research: As a tool compound for studying its interactions with biological receptors and enzymes relevant to neurological function.
• Natural Product Isolation & Analysis: Serving as a benchmark for the identification and quantification of Corybulbine in plant extracts and traditional medicine preparations.
• Academic & Institutional Research: For chemical education and fundamental research in organic chemistry and alkaloid biosynthesis.

Basic Information

Product Name	Corybulbine
CAS No.	518-77-4
Molecular Formula	C20H23NO4
Molecular Weight	341.40 g/mol
Synonyms	(-)-Corybulbine; (S)-Corybulbine; L-Corybulbine; 5,8,13,13a-Tetrahydro-2,3,10-trimethoxy-6H-dibenzo[a,g]quinolizine-1,9-diol; Bulbocapnine methyl ether; Corydalis alkaloid
EINECS	Contact for details

Quality Control

Our Corybulbine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.