Description

3,12-Didehydro-2β,9,10-Trimethoxygalanthan-1α-Ol CAS NO 517-78-2 is a high-purity galanthamine-type alkaloid derivative, recognized for its complex heterocyclic structure. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of neurological pathways. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors. Its precise chemical architecture makes it valuable for synthesizing novel bioactive molecules and for analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced galanthamine analogs and other neurologically active compounds.
• Reference Standard: Used as a high-purity calibrant in analytical chemistry for method validation and quality control in pharmaceutical labs.
• Biochemical Research: Employed in academic and industrial R&D to study acetylcholinesterase inhibition and related neurological mechanisms.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex alkaloid-based active pharmaceutical ingredients (APIs).
• Standards Manufacturing: A source material for companies producing certified reference materials (CRMs) for the pharmaceutical industry.

Basic Information

Product Name	3,12-Didehydro-2β,9,10-Trimethoxygalanthan-1α-Ol
CAS No.	517-78-2
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	Lycoramine, N-Demethylgalanthamine; 1,2-Didehydrolycoramine; 2,9,10-Trimethoxy-3,12-didehydrogalanthan-1-ol; Galanthamine Impurity; 3,12-Didehydro-2β,9,10-trimethoxygalanthan-1α-ol; Lycoramine Derivative
EINECS	Contact for details

Quality Control

Our 3,12-Didehydro-2β,9,10-Trimethoxygalanthan-1α-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and should be handled under inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.