Description

Taurodehydrocholate is a conjugated bile acid derivative, formed by the conjugation of dehydrocholic acid with taurine. This compound is of significant interest in biochemical and pharmaceutical research due to its role in studying bile acid metabolism, transport, and receptor interactions. It serves as a critical intermediate and reference standard for scientists and manufacturers in the life sciences sector. Key industries that utilize this specialty chemical include pharmaceutical R&D, diagnostic reagent production, and academic research institutions.

Application

• Pharmaceutical Research & Development: Used as a reference standard and intermediate in the synthesis of novel therapeutic agents targeting bile acid pathways.
• Biochemical Studies: Employed in research on bile acid transporters (e.g., ASBT, NTCP), metabolic enzymes, and nuclear receptors like FXR.
• Diagnostic Reagents: Acts as a key component in the formulation of calibration standards and assay kits for liver function and metabolic disorder diagnostics.
• Cell Culture & Membrane Studies: Utilized to investigate membrane fluidity, solubilization, and the formation of micelles in in vitro models.
• Academic Research: Serves as a tool compound in university and institutional labs for fundamental studies in gastroenterology and hepatology.

Basic Information

Product Name	Taurodehydrocholate
CAS No.	517-37-3
Molecular Formula	C₂₆H₄₃NO₇S
Molecular Weight	513.69 g/mol
Synonyms	Dehydrotaurocholic acid; Taurodehydrocholic acid; 3,7,12-Trioxo-5β-cholan-24-oyltaurine; N-(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)taurine; Tauroursodeoxycholate impurity; Bile acid conjugate; Taurine conjugate of dehydrocholate
EINECS	208-250-1

Quality Control

Our Taurodehydrocholate is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent in-house specifications. We support research and production needs with material traceability and documentation suitable for cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.