Description

Allopregnandiol is a significant endogenous neurosteroid and a key metabolite in the biosynthesis of other steroid hormones. This compound is crucial for research and development in the life sciences, serving as a vital reference standard and intermediate. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of diagnostic reagents for investigating neuroactive steroid pathways and hormone-related disorders.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, GC-MS) for drug development and bioanalytical studies.
• Neurosteroid Research: Critical for studying the modulation of GABA-A receptors, neuronal excitability, and related neurological conditions.
• Biochemical Intermediate: Serves as a key precursor or intermediate in the synthetic pathways of other therapeutic steroid compounds.
• Diagnostic Reagent Manufacturing: Employed in the production of immunoassay kits and other diagnostic tools for measuring steroid hormone levels.
• Endocrinology Studies: Facilitates research into steroid metabolism, hormone biosynthesis, and endocrine system function.
• Academic & Institutional Research: Supports basic scientific research in universities and government labs focused on steroid biology and pharmacology.

Basic Information

Item	Detail
Product Name	Allopregnandiol
CAS No.	516-53-0
Molecular Formula	C21H36O2
Molecular Weight	320.51 g/mol
Synonyms	5α-Pregnane-3α,20α-diol; 3α,20α-Allopregnanediol; 3α,20α-Dihydroxy-5α-pregnane; 20α-Hydroxy-5α-pregnan-3α-ol; Allopregnanediol; 5α-Pregnan-3α,20α-diol
EINECS	208-231-5

Quality Control

Our Allopregnandiol is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.