Description

α-Cortol CAS NO 516-38-1 is a specific steroid metabolite of interest in biochemical research and pharmaceutical development. This compound is valued for its role as a reference standard in analytical chemistry and as a key intermediate in the synthesis of more complex steroid-based molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and manufacturers of high-purity fine chemicals.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of steroid metabolites in research and quality control laboratories.
• Biochemical Research: Serves as a crucial intermediate or substrate in studies of steroid hormone metabolism and enzymatic pathways.
• Fine Chemical Synthesis: Acts as a building block for the synthesis of more complex steroid derivatives and potential active pharmaceutical ingredients (APIs).
• Diagnostic Development: Employed in the development and calibration of diagnostic assays, particularly those related to endocrine function and metabolic disorders.
• Academic Research: Used in university and institutional labs for fundamental studies in organic chemistry, biochemistry, and pharmacology.

Basic Information

Product Name	α-Cortol
CAS No.	516-38-1
Molecular Formula	C21H34O5
Molecular Weight	366.49 g/mol
Synonyms	5β-Pregnane-3α,11β,17α,20α,21-Pentol; (3α,5β,11β,17α,20α)-3,11,17,20,21-Pentahydroxypregnane; 11β,17α,20α,21-Tetrahydroxy-5β-pregnan-3-one (reduced form); α-Cortol; 5β-Cortol; Tetrahydrocortisol (isomer); Cortol (α-isomer); 3α,5β-Tetrahydrocortisol
EINECS	Contact for details

Quality Control

Our α-Cortol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Optical Rotation	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.