Description

9-cis-Retinal is a vital isomer of vitamin A aldehyde, playing a crucial role in the visual cycle as the chromophore of the photoreceptor protein, rhodopsin. This high-purity biochemical is essential for research and development in vision science, photobiology, and the study of retinoid signaling pathways. It is a key material for pharmaceutical R&D, academic research institutions, and manufacturers of advanced biochemical reagents and diagnostic kits.

Application

• Vision Science Research: Fundamental studies on the biochemistry of vision, including the photoisomerization processes within rhodopsin and cone opsins.
• Photobiology & Biophysics: Investigation of light-induced protein conformational changes and signal transduction mechanisms.
• Pharmaceutical R&D: A critical intermediate and reference standard in the development of novel retinoid-based therapeutics for ophthalmic and dermatological conditions.
• Biochemical Reagent Manufacturing: Used in the production of high-grade reagents, assay kits, and standards for life science research and clinical diagnostics.
• Nutraceutical Research: Studies on the metabolism, bioavailability, and physiological roles of different vitamin A isomers.
• Material Science: Exploration in bio-inspired materials and molecular switches due to its light-responsive properties.

Basic Information

Product Name	9-cis-Retinal
CAS No.	514-85-2
Molecular Formula	C₂₀H₂₈O
Molecular Weight	284.44 g/mol
Synonyms	9-cis-Retinaldehyde; (9Z)-Retinal; 9Z-Retinal; neo-b-Retinal; 9-cis-Vitamin A Aldehyde; (9Z)-Retinaldehyde; 9-cis-Retinene; 9-cis-Retinal (Vitamin A Aldehyde)
EINECS	208-187-2

Quality Control

Our 9-cis-Retinal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is rigorously analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and isomer specificity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (9-cis isomer)
Isomeric Purity (HPLC)	≤ 2.0% total related isomers (all-trans, 13-cis, etc.)
Solubility	Soluble in ethanol, DMSO, chloroform; insoluble in water
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.