Description

Isochlortetracyclinehydrochloride CAS NO 514-53-4 is a chemically modified derivative of the tetracycline class of antibiotics, valued for its potent antimicrobial activity. This compound is critical for research and development in the pharmaceutical sector, particularly for studying antibiotic mechanisms and resistance. It serves as a key intermediate and reference standard for manufacturers and research institutions focused on developing novel antimicrobial agents and analytical methods.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the synthesis and study of novel tetracycline-class antibiotics.
• Microbiological Studies: Used in laboratory research to investigate bacterial growth inhibition, mechanisms of antibiotic action, and the development of antimicrobial resistance.
• Veterinary Medicine Development: Employed in the R&D of broad-spectrum antibacterial treatments for animal health.
• Analytical Chemistry: Serves as a high-purity calibration standard in HPLC, LC-MS, and other chromatographic methods for quality control in pharmaceutical analysis.
• Biochemical Reagent: Utilized in cell culture and molecular biology experiments to selectively control bacterial contamination in research settings.

Basic Information

Product Name	Isochlortetracyclinehydrochloride
CAS No.	514-53-4
Molecular Formula	C₂₂H₂₃ClN₂O₈ • HCl
Molecular Weight	515.34 g/mol
Synonyms	Isochlorotetracycline Hydrochloride; 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride; Isochlortetracycline HCl; 7-Chlorotetracycline Hydrochloride Isomer; Antibiotic X-340A Hydrochloride; Aureomycin Isomer Hydrochloride
EINECS	208-187-0

Quality Control

Our Isochlortetracyclinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR spectroscopy, purity assay by HPLC, and control of related substances and residual solvents, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.