Description

Ecothiopate Iodide is a potent organophosphate compound primarily recognized for its pharmacological activity as a long-acting cholinesterase inhibitor. This high-purity active pharmaceutical ingredient (API) is critical for research and development in ophthalmology and neurological studies. It is essential for manufacturers and research institutions focused on developing treatments for conditions like glaucoma and for investigating cholinergic signaling pathways.

Application

• Ophthalmic Pharmaceutical Formulations: Used as the active ingredient in miotic agents for the management of chronic open-angle glaucoma and accommodative esotropia.
• Neurological Research: Serves as a key tool compound in preclinical studies to investigate the effects of sustained cholinesterase inhibition on the central and peripheral nervous systems.
• Biochemical Assay Development: Employed as a standard or reference material in developing and validating in-vitro enzymatic assays for acetylcholinesterase activity.
• Veterinary Medicine Research: Investigated for potential applications in veterinary ophthalmology for similar ophthalmic conditions in animals.
• Chemical Synthesis Intermediate: Acts as a specialized intermediate in the synthesis of novel organophosphate derivatives for pharmacological screening.

Basic Information

Product Name	Ecothiopate Iodide
CAS No.	513-10-0
Molecular Formula	C9H23INO3PS
Molecular Weight	383.23 g/mol
Synonyms	Echothiophate Iodide; Phospholine Iodide; Diethyl (2-diethylaminoethyl)phosphorothioate methiodide; (2-Diethylaminoethyl)diethylphosphorothioate methiodide; Ecothiopate; Echotiophate; Echodide; Ecostigmine Iodide
EINECS	208-163-8

Quality Control

Our Ecothiopate Iodide is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and specific tests for residual solvents and heavy metals. We provide full traceability and a Certificate of Analysis (COA) with each shipment, ensuring compliance with relevant guidelines for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.