Description

Cyclopentolate is a potent anticholinergic agent belonging to the class of synthetic muscarinic antagonists. This compound is of significant commercial and pharmaceutical importance due to its specific action as a mydriatic and cycloplegic. It is primarily required by manufacturers in the ophthalmic pharmaceutical sector for the formulation of diagnostic and therapeutic eye drops.

Application

• Ophthalmic Solutions: As the active pharmaceutical ingredient (API) in eye drops for diagnostic eye examinations.
• Mydriasis Induction: Used to dilate the pupil (mydriasis) for fundoscopic examination and other diagnostic procedures.
• Cycloplegia Induction: Employed to temporarily paralyze the ciliary muscle (cycloplegia) for accurate refractive error measurement.
• Uveitis Treatment: Component in therapeutic regimens to treat inflammatory conditions of the uvea.
• Pre-operative Preparation: Used prior to certain ocular surgeries to achieve optimal pupil dilation.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate for related anticholinergic compounds.
• Research & Development: Utilized in biochemical and pharmacological research studying muscarinic receptor function.

Basic Information

Product Name	Cyclopentolate
CAS No.	512-15-2
Molecular Formula	C17H25NO3
Molecular Weight	291.39 g/mol
Synonyms	Cyclopentolate Hydrochloride (common salt form); 2-(Dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate; Cyclogyl; AK-Pentolate; Pentolair; Cyclate; Oftan-Syklo; Cyclopentol; Cyclopentolate HCl; 1-Hydroxy-α-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester
EINECS	208-129-5

Quality Control

Our Cyclopentolate is manufactured under strict quality management systems, targeting compliance with pharmacopeial standards such as USP and EP. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and regulatory support for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.