Description

(8Alpha)-12'-Hydroxy-5'α-Isobutyl-2'-Isopropylergotaman-3',6',18-Trione is a complex ergot alkaloid derivative, a class of compounds known for their intricate polycyclic structures and significant biological activity. This specific derivative is of high interest in advanced pharmaceutical research and development due to its unique structural modifications. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector, particularly those developing or analyzing novel therapeutic agents targeting neurological and vascular systems.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control in drug substance and product testing.
• Biochemical Research: Employed in academic and industrial laboratories to study the structure-activity relationships (SAR) of ergot alkaloids and their interaction with biological targets.
• Advanced Intermediate: Acts as a key synthetic building block for the preparation of more complex, pharmacologically active molecules in medicinal chemistry programs.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway research to identify and characterize drug metabolites.

Basic Information

Product Name	(8Alpha)-12'-Hydroxy-5'α-Isobutyl-2'-Isopropylergotaman-3',6',18-Trione
CAS No.	511-10-4
Molecular Formula	C32H41N5O5
Molecular Weight	575.70 g/mol
Synonyms	12'-Hydroxy-5'α-isobutyl-2'α-isopropylergotaman-3',6',18-trione; 12'-Hydroxy-5'α-isobutyl-2'α-isopropyl-3',6',18-trioxoergotaman; Ergotaman-3',6',18-trione, 12'-hydroxy-5'α-isobutyl-2'α-isopropyl-; (8α)-12'-Hydroxy-5'α-isobutyl-2'α-isopropylergotaman-3',6',18-trione; A derivative of ergotaman.
EINECS	Contact for details

Quality Control

Our (8Alpha)-12'-Hydroxy-5'α-Isobutyl-2'-Isopropylergotaman-3',6',18-Trione is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) providing batch-specific data is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.