Description

Ergocristine is a potent ergot alkaloid of significant interest in pharmaceutical research and development. Its unique chemical structure makes it a valuable reference standard and a key intermediate in the synthesis of more complex therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies focused on neurology, vascular biology, and drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of ergot alkaloids in drug substances and finished products.
• Biochemical Research: Serves as a critical tool in studies investigating serotonin and dopamine receptor interactions.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key building block in the synthesis of more complex, pharmacologically active ergot derivatives.
• Analytical Method Development: Employed in the validation and calibration of HPLC, LC-MS, and other chromatographic systems for ergot alkaloid detection.
• Quality Control Laboratories: Essential for ensuring the purity and identity of related substances in pharmaceutical manufacturing.

Basic Information

Product Name	Ergocristine
CAS No.	511-08-0
Molecular Formula	C35H39N5O5
Molecular Weight	609.72 g/mol
Synonyms	Ergocristine; Dihydroergocristine; 9,10-Dihydroergocristine; 12'-Hydroxy-2',5'-bis(1-methylethyl)ergotaman-3',6',18-trione; (8β)-Ergoline-8-carboxamide; Ergotaman-3',6',18-trione, 12'-hydroxy-2',5'-bis(1-methylethyl)-, (5'α)-; NSC 524051
EINECS	208-120-5

Quality Control

Our Ergocristine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.