Description

(8Alpha)-5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione is a complex ergot alkaloid derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by advanced research institutions and pharmaceutical manufacturers specializing in central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel ergot-based pharmaceuticals.
• Biochemical Research: Used as a reference standard or probe in studies of serotonin and dopamine receptor interactions.
• Precursor for Active Pharmaceutical Ingredients (APIs): Serves in the development pathway for potential treatments targeting migraines, Parkinson's disease, and other neurological conditions.
• Academic & Contract Research: Employed in university and CRO laboratories for pharmacological and metabolic pathway studies.
• Process Chemistry Development: Used to optimize synthetic routes and scale-up processes for complex alkaloid derivatives.

Basic Information

Product Name	(8Alpha)-5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione
CAS No.	511-07-9
Molecular Formula	C32H37N3O5
Molecular Weight	543.66 g/mol
Synonyms	5'-Benzyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione; 5'-Benzyl-12'-hydroxy-2'-(1-methylethyl)ergotaman-3',6',18-trione; 8α-5'α-Benzyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione; Ergotaman-3',6',18-trione, 5'-benzyl-12'-hydroxy-2'-(1-methylethyl)-, (8α)-; 5'-Benzyl-12'-hydroxy-2'-isopropyl-8α-ergotaman-3',6',18-trione; 511-07-9; 8α-5'α-Benzyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione
EINECS	Contact for details

Quality Control

Our (8Alpha)-5'α-Benzyl-12'-Hydroxy-2'-Isopropylergotaman-3',6',18-Trione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.