Description

(-)-Crinine【C16 Alkaloid】 is a naturally occurring isoquinoline alkaloid isolated from plants of the Amaryllidaceae family, such as *Crinum* species. This chiral compound serves as a valuable phytochemical reference standard and a key synthetic intermediate for medicinal chemistry research. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors for drug discovery and development programs targeting neurological and other therapeutic areas.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Amaryllidaceae alkaloids in drug discovery and quality control laboratories.
• Medicinal Chemistry Research: Serves as a core scaffold or intermediate for the synthesis of novel analogs with potential biological activity.
• Biological Activity Screening: Employed in in vitro and in vivo studies to investigate its acetylcholinesterase inhibitory, anti-cancer, or anti-inflammatory properties.
• Natural Product Isolation & Authentication: Acts as a critical benchmark in the isolation, identification, and characterization of related alkaloids from plant extracts.
• Analytical Method Development: Utilized to develop and validate chromatographic (HPLC, LC-MS) methods for alkaloid profiling.

Basic Information

Product Name	(-)-Crinine【C16 Alkaloid】
CAS No.	510-67-8
Molecular Formula	C16H17NO3
Molecular Weight	271.31 g/mol
Synonyms	(-)-Crinine; Crinine; (3S,5aR,9bS)-5-Ethyl-3,5a,6,7,8,9,9a,9b-octahydro-3-methyl-1H-benz[e]indol-8-ol; 8-Hydroxycrinane; Amaryllidaceae Alkaloid; 1H-Benz[e]indol-8-ol, 5-ethyl-3,5a,6,7,8,9,9a,9b-octahydro-3-methyl-, (3S,5aR,9bS)-
EINECS	Contact for details

Quality Control

Our (-)-Crinine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.