Description

1-o-Hexadecyl-Sn-Glycerol is a synthetic, enantiomerically pure alkyl glyceryl ether, a key building block in lipid chemistry and biochemistry. This compound is valued for its role as a precursor in the synthesis of complex ether lipids, platelet-activating factor (PAF) analogs, and other bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries developing advanced lipid-based formulations and drug delivery systems.

Application

• Pharmaceutical Intermediate: Critical precursor for the synthesis of platelet-activating factor (PAF) analogs and other ether-linked phospholipids with biological activity.
• Lipid Research: Used as a standard and building block in academic and industrial research on lipid metabolism, membrane biophysics, and signaling pathways.
• Cosmetic Formulations: Serves as a base material for creating skin-compatible emulsifiers and moisturizing agents in high-end skincare products.
• Drug Delivery Systems: Incorporated into the design of liposomes and other nanocarriers to modify membrane fluidity and targeting properties.
• Biochemical Tools: Utilized in the development of fluorescent or tagged lipid probes for cellular imaging and diagnostic assays.
• Specialty Surfactants: Acts as a key intermediate for producing non-ionic surfactants with specific hydrophilic-lipophilic balance (HLB) values.

Basic Information

Product Name	1-o-Hexadecyl-Sn-Glycerol
CAS No.	506-03-6
Molecular Formula	C19H40O3
Molecular Weight	316.52 g/mol
Synonyms	1-O-Hexadecyl-sn-glycerol; (2R)-2,3-Dihydroxypropyl hexadecyl ether; sn-3-O-Hexadecylglycerol; 1-O-Cetyl-sn-glycerol; Hexadecyl glyceryl ether; Chimyl alcohol (enantiomer); Alkyl glyceryl ether C16:0; AGEPC precursor; PAF precursor
EINECS	208-043-6

Quality Control

Our 1-o-Hexadecyl-Sn-Glycerol is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as enantiomeric excess, chemical purity, and identity confirmation. We adhere to relevant industry standards and can provide material suitable for research and development under controlled conditions.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation. The material should be kept in a cool, dry place away from strong oxidizing agents. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity	≥ 98.0% (sn-1 isomer)
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.