Description

Mevalonolactone is a key lactone derivative and a vital intermediate in the biosynthesis of isoprenoids, including cholesterol and other sterols. Its high purity and consistent quality make it an essential building block for advanced pharmaceutical research and fine chemical synthesis. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for developing therapeutic agents and studying metabolic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of statins and other cholesterol-lowering drugs.
• Biochemical Research: Used as a substrate or standard in studies of the mevalonate pathway and isoprenoid biosynthesis.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for producing complex organic molecules and active pharmaceutical ingredients (APIs).
• Nutraceutical Development: Investigated for use in the research and development of dietary supplements targeting metabolic health.
• Enzymology Studies: Employed in assays to study the activity of enzymes like mevalonate kinase.
• Cosmetic Ingredient Research: Explored for potential applications in skincare formulations due to its role in cellular metabolism.

Basic Information

Product Name	Mevalonolactone
CAS No.	503-48-0
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	Mevalonic acid lactone; 3-Hydroxy-3-methylpentanoic acid δ-lactone; (R)-Mevalonolactone; D-Mevalonolactone; 3-Methyl-3-hydroxy-pentanoic acid lactone; 5-Methyl-5-hydroxy-dihydro-furan-2-one; 3-Hydroxy-3-methylvalerolactone; NSC 37447
EINECS	207-966-0

Quality Control

Our Mevalonolactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range available on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.