Description

Broxuridine is a halogenated nucleoside analog widely used as a research chemical and a key intermediate in pharmaceutical synthesis. Its primary value lies in its ability to act as a thymidine analog, making it a vital tool for studying DNA replication, cell proliferation, and as a potential radiosensitizer in oncology research. This compound is essential for research institutions, pharmaceutical R&D departments, and manufacturers of diagnostic reagents and fine chemicals.

Application

• Biomedical Research: Used as a thymidine analog for labeling newly synthesized DNA in cell proliferation and cytotoxicity assays.
• Oncology Studies: Investigated for its potential as a radiosensitizing agent in cancer therapy research.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex nucleoside-based antiviral or anticancer agents.
• Diagnostic Reagent Manufacturing: Employed in the production of kits and reagents for cell cycle analysis and molecular biology.
• Cell Biology: Utilized in pulse-chase experiments to track DNA synthesis and cell lineage.
• Virology Research: Applied in studies of viral replication mechanisms that involve host cell DNA synthesis.

Basic Information

Product Name	Broxuridine
CAS No.	59-14-3
Molecular Formula	C9H11BrN2O5
Molecular Weight	307.10 g/mol
Synonyms	5-Bromo-2'-deoxyuridine; BrdU; 5-BrdUrd; Broxuridine; BUdR; 5-Bromodeoxyuridine; NSC 38297; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-dione
EINECS	200-415-9

Quality Control

Our Broxuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.