Description

11-β-Hydroxyandrosterone is a significant metabolite of testosterone and a key intermediate in steroid hormone biosynthesis. This compound is crucial for research and development in endocrinology and pharmaceutical manufacturing, providing a high-purity reference standard for analytical and synthetic applications. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of diagnostic reagents and steroid-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and qualification of steroid metabolites in analytical methods like HPLC and LC-MS.
• Biochemical Research: Serves as a critical intermediate in studying androgen metabolism, enzyme activity (e.g., 11β-HSD), and related metabolic pathways.
• Diagnostic Kit Manufacturing: Employed in the production of calibration standards and controls for clinical diagnostic assays measuring steroid hormone levels.
• API Synthesis: Acts as a key chiral building block or precursor in the synthetic routes of more complex steroid-based therapeutic agents.
• Metabolite Profiling: Essential for doping control laboratories and forensic toxicology for the accurate identification of endogenous steroid profiles.

Basic Information

Product Name	11-β-Hydroxyandrosterone
CAS No.	57-61-4
Molecular Formula	C19H30O3
Molecular Weight	306.44 g/mol
Synonyms	11β-Hydroxyandrosterone; 3α,11β-Dihydroxy-5α-androstan-17-one; 11β-Hydroxy-3α-hydroxy-5α-androstan-17-one; 11β-OH-Androsterone; 11β-Hydroxyetiocholanolone (related isomer); 11-Hydroxyandrosterone; Androsterone, 11β-hydroxy-; NSC 11319
EINECS	200-347-8

Quality Control

Our 11-β-Hydroxyandrosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by infrared spectroscopy (IR), assay by high-performance liquid chromatography (HPLC), and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.