Description

5-Hydroxyindole-3-Acetic Acid CAS NO 54-16-0 is a key indole derivative and a major metabolite of the neurotransmitter serotonin. This compound is of significant importance in biochemical research and pharmaceutical development, serving as a critical reference standard and analytical marker. It is primarily needed by research institutions, diagnostic laboratories, and pharmaceutical companies engaged in neurochemistry, metabolic studies, and the development of assays for serotonin-related disorders.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in the study of serotonin metabolism and indole pathways.
• Diagnostic Reagent Manufacturing: A critical component in the production of diagnostic kits for quantifying serotonin metabolites in biological fluids (e.g., urine, plasma).
• Pharmaceutical Intermediate: Serves as a key synthetic building block or precursor in the development of novel neuroactive compounds and pharmaceuticals.
• Analytical Chemistry: Employed as an internal standard or calibrant in chromatographic methods (HPLC, LC-MS) for accurate quantification of related analytes.
• Metabolic Pathway Studies: Essential for in vitro and in vivo research investigating the catabolism of serotonin and related physiological processes.
• Quality Control (QC) in Pharma: Used in the quality assurance and control of pharmaceutical products targeting the serotonergic system.

Basic Information

Product Name	5-Hydroxyindole-3-Acetic Acid
CAS No.	54-16-0
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	5-HIAA; 5-Hydroxyindol-3-ylacetic Acid; 5-Hydroxy-3-indoleacetic Acid; 3-(5-Hydroxy-1H-indol-3-yl)acetic Acid; 5-Hydroxyskatolecarboxylic Acid; Serotonin Metabolite; 5-Hydroxyindoleacetate
EINECS	200-192-0

Quality Control

Our 5-Hydroxyindole-3-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.