Description

6 β-Hydroxycortisol is a significant metabolite of cortisol, offering a critical reference standard for biochemical research and diagnostic applications. This compound is essential for studies investigating steroid metabolism, endocrine function, and related metabolic pathways. It is primarily utilized by research institutions, pharmaceutical developers, and clinical diagnostic laboratories requiring high-purity analytical standards.

Application

• Biochemical Research Standard: Serves as a high-purity reference material for the study of cortisol metabolism and steroidogenesis.
• Endocrinology Studies: Used in research focused on adrenal function, stress response, and hormonal regulation.
• Diagnostic Assay Development: Acts as a critical calibrant or control in the development of immunoassays and LC-MS/MS methods for hormone analysis.
• Pharmaceutical Metabolite Analysis: Employed in drug development to study the metabolic fate of corticosteroid-based pharmaceuticals.
• Clinical Research: Utilized in investigations linking cortisol metabolism to various physiological and pathological conditions.
• Quality Control: Functions as an in-house standard for ensuring the accuracy and precision of analytical methods in testing laboratories.

Basic Information

Product Name	6 β-Hydroxycortisol
CAS No.	53-35-0
Molecular Formula	C₂₁H₃₀O₆
Molecular Weight	378.46 g/mol
Synonyms	6β-Hydroxycortisol; 6β-Hydroxyhydrocortisone; 11β,17α,21-Trihydroxy-6β-pregn-4-ene-3,20-dione; (6β,11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione; Cortisol 6β-ol; 6β-Hydroxycortisol; 6β-OH-F
EINECS	200-173-5

Quality Control

Our 6 β-Hydroxycortisol is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC and NMR, to ensure it meets the high standards required for research and diagnostic use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.