Description

Floxuridine is a fluorinated pyrimidine nucleoside analog, a critical pharmaceutical intermediate and active pharmaceutical ingredient (API) with the CAS registry number 50-91-9. Its primary value lies in its potent antimetabolite activity, which interferes with DNA synthesis and cell replication. This compound is essential for manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development and production of oncology therapeutics.

Application

• Oncology Drug Manufacturing: As an active pharmaceutical ingredient (API) in the formulation of injectable chemotherapeutic agents.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex anticancer compounds and prodrugs.
• Biochemical Research: Used as a reference standard and tool compound in cancer research, cell biology, and molecular pharmacology studies.
• Antiviral Research: Investigated for its potential application in antiviral therapies due to its mechanism of action.
• Radiopharmaceuticals: Potential use as a precursor in the development of radiolabeled compounds for diagnostic imaging.

Basic Information

Product Name	Floxuridine
CAS No.	50-91-9
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19 g/mol
Synonyms	5-Fluoro-2'-deoxyuridine; 5-Fluoro-2'-deoxyuridine; 5-FUdR; FUDR; 2'-Deoxy-5-fluorouridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-fluorouracil; NSC-27640; Floxuridinum; Floxuridin
EINECS	200-072-5

Quality Control

Our Floxuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) detailing specifications for identity, purity, and impurities, referencing pharmacopeial methodologies where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.