Description

6-Mercaptopurine is a thiopurine derivative and a purine analogue with significant biochemical activity. This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of various chemotherapeutic agents. It is primarily required by the pharmaceutical industry for the production of medications used in oncology and immunology. Our supply ensures high purity and consistent quality for demanding research and manufacturing applications.

Application

• Oncological Pharmaceuticals: As an active pharmaceutical ingredient (API) in the manufacture of chemotherapy drugs for treating acute lymphoblastic leukemia (ALL) and other cancers.
• Immunosuppressive Therapies: Used in medications to manage autoimmune diseases such as Crohn's disease and ulcerative colitis.
• Biochemical Research: Serves as a crucial tool compound in cancer research, studying purine metabolism, apoptosis, and cell proliferation mechanisms.
• Pharmaceutical Intermediates: Acts as a key building block in the synthesis of more complex thiopurine-based drug molecules.
• Reference Standards: Supplied as a high-purity certified reference material (CRM) for analytical testing and quality control in pharmaceutical laboratories.

Basic Information

Product Name	6-Mercaptopurine
CAS No.	50-44-2
Molecular Formula	C5H4N4S
Molecular Weight	152.18 g/mol
Synonyms	6-MP; Mercaptopurine; Purinethol; 1,7-Dihydro-6H-purine-6-thione; 6-Thiohypoxanthine; 6-Thiopurine; Leukerin; Puri-Nethol; 6-Hydroxy-2-mercaptopurine; NSC-755
EINECS	200-045-7

Quality Control

Our 6-Mercaptopurine is manufactured and tested under a strict quality management system. We offer grades suitable for pharmaceutical applications, with specifications that can meet or exceed relevant pharmacopoeial standards (e.g., USP, EP). Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure supply reliability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.