Description

n-3-Oxo-Hexadec-11Z-Enoyl-L-Homoserine Lactone is a specialized N-acyl homoserine lactone (AHL) derivative, a key class of signaling molecules in bacterial quorum sensing. This compound is of significant interest for its role in mediating intercellular communication in Gram-negative bacteria, influencing biofilm formation, virulence, and other population-dependent behaviors. It is a critical research tool for microbiologists, synthetic biologists, and pharmaceutical developers working on novel anti-infective strategies and bio-control agents.

Application

• Quorum Sensing Research: Used as a standard or probe to study and manipulate bacterial communication pathways in model organisms like Pseudomonas aeruginosa.
• Anti-Virulence Drug Discovery: Serves as a lead compound or antagonist in high-throughput screening assays to identify novel agents that disrupt biofilm formation and pathogenicity.
• Agricultural Biotechnology: Applied in research to develop biocontrol strategies that interfere with the quorum sensing of plant pathogens, offering potential alternatives to traditional pesticides.
• Synthetic Biology: Acts as a key signaling molecule in engineered microbial consortia for controlled gene expression and synchronized population behaviors.
• Biomedical Material Coating: Investigated for surface functionalization to prevent bacterial colonization on medical implants and devices.
• Environmental Microbiology: Used to study and potentially control microbial community dynamics in wastewater treatment and bioremediation processes.

Basic Information

Product Name	n-3-Oxo-Hexadec-11Z-Enoyl-L-Homoserine Lactone
CAS No.	479050-91-4
Molecular Formula	C20H33NO4
Molecular Weight	351.48 g/mol
Synonyms	N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-11Z-hexadecenamide; 3-Oxo-C12-HSL (3-oxo-dodecanoyl homoserine lactone) analog; 3-Oxo-N-(tetrahydro-2-oxo-3-furanyl)-11Z-hexadecenamide; (S)-N-(3-Oxotetrahydrofuran-2-yl)-11Z-hexadecenamide; AHL C16:1(11Z)-3-oxo; Quorum Sensing Molecule C16; N-Acyl Homoserine Lactone Derivative; Bacterial Signaling Molecule
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure high purity and batch-to-batch consistency, which is critical for reproducible research results. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to strict in-house quality standards suitable for research and development applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Under these conditions, the product is typically stable for at least 24 months. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.