Description

2-[1-13C]Acetamido-2-Deoxy-D-Glucose is a stable isotope-labeled analog of N-acetylglucosamine, a fundamental building block in glycobiology and metabolic research. This compound is essential for advanced analytical studies, providing a non-radioactive tracer for precise metabolic pathway elucidation and quantification using techniques like mass spectrometry and NMR. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic companies engaged in carbohydrate metabolism, glycosylation studies, and biomarker discovery.

Application

• Metabolic Flux Analysis (MFA): As a 13C-labeled tracer for studying glucoseamine metabolism in cell cultures and model organisms.
• Glycoprotein & Glycolipid Research: Used to trace and quantify the incorporation of N-acetylglucosamine into complex glycans and glycoconjugates.
• Biomarker Development: Serves as an internal standard in LC-MS/MS and GC-MS methods for the accurate quantification of related metabolites in biological fluids.
• Pharmaceutical R&D: Employed in drug discovery programs targeting metabolic disorders, cancer metabolism, and infectious diseases involving chitin or glycoprotein synthesis.
• Enzymology Studies: A substrate for investigating the kinetics and mechanisms of enzymes like hexokinases and glycosyltransferases.

Basic Information

Product Name	2-[1-13C]Acetamido-2-Deoxy-D-Glucose
CAS No.	478518-87-5
Molecular Formula	C8H1513CNO6
Molecular Weight	222.66 g/mol (for 13C1 isotopologue)
Synonyms	2-Acetamido-2-deoxy-D-[1-13C]glucose; N-Acetyl-D-[1-13C]glucosamine; [1-13C]-GlcNAc; 2-(Acetylamino)-2-deoxy-D-[1-13C]glucose; D-[1-13C]N-Acetylglucosamine; Stable Isotope Labeled N-Acetylglucosamine; 13C1-GlcNAc
EINECS	Contact for details

Quality Control

Our 2-[1-13C]Acetamido-2-Deoxy-D-Glucose is manufactured under controlled conditions to ensure high isotopic and chemical purity, critical for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to stringent in-house quality standards suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.