Description

[2'-13C]Cytidine CAS NO 478511-19-2 is a stable isotope-labeled analog of the nucleoside cytidine, specifically enriched with carbon-13 at the 2' position of the ribose sugar. This precise labeling makes it an indispensable tool for advanced metabolic flux analysis, pharmacokinetic studies, and the synthesis of isotopically-labeled oligonucleotides. It is primarily required by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers engaged in tracer studies, NMR spectroscopy, and mass spectrometry-based proteomics.

Application

• Metabolic Tracer Studies: Used to track nucleotide and nucleic acid metabolism in cell cultures and animal models.
• NMR Spectroscopy: Serves as a crucial internal standard or probe for structural and dynamic studies of RNA and related biomolecules.
• Mass Spectrometry (MS) Standards: Employed as an internal standard for the accurate quantification of cytidine and its derivatives in LC-MS/MS platforms.
• Pharmaceutical Research: Utilized in the development and testing of antiviral and anticancer nucleoside analogs.
• Synthesis of Labeled Oligonucleotides: Acts as a building block for the production of 13C-labeled DNA or RNA probes for advanced research applications.
• Biochemical Pathway Analysis: Enables detailed investigation of the de novo and salvage pathways of pyrimidine biosynthesis.

Basic Information

Product Name	[2'-13C]Cytidine
CAS No.	478511-19-2
Molecular Formula	C9[13C]H13N3O5
Molecular Weight	244.21 g/mol (for 13C1 labeled)
Synonyms	2'-13C-Cytidine; 1-β-D-Ribofuranosyl-2'-13C-cytosine; Cytidine-2'-13C; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((2'-13C)hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 13C Labeled Cytidine; Isotopic Cytidine; Cytidine (2'-13C)
EINECS	Contact for details

Quality Control

Every batch of [2'-13C]Cytidine is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (NMR/HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.