Description

D-Erythro-Sphingosine (Brain, Porcine) is a high-purity, naturally derived sphingolipid backbone molecule. This compound is a critical biochemical tool and intermediate for research and development in lipidomics, cell signaling, and pharmaceutical synthesis. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced life science research sectors who require a reliable, high-quality source for studying apoptosis, cell proliferation, and metabolic pathways.

Application

• Biochemical Research: Fundamental studies on sphingolipid metabolism, cell signaling cascades, and ceramide synthesis pathways.
• Pharmaceutical Development: Serving as a key chiral intermediate or reference standard in the synthesis of novel therapeutics targeting cancer, inflammation, and neurological disorders.
• Cell Biology & Diagnostics: Used in assays to investigate cell growth, differentiation, and programmed cell death (apoptosis).
• Lipidomics Standard: Acts as a certified reference material (CRM) for the qualitative and quantitative analysis of complex lipid samples via LC-MS or GC-MS.
• Enzyme Substrate: Employed in enzymatic studies for kinases and other enzymes involved in the sphingolipid metabolic network.
• Cosmeceutical R&D: Exploration of bioactive lipid compounds for advanced skincare formulations targeting cellular repair and barrier function.

Basic Information

Product Name	D-Erythro-Sphingosine (Brain, Porcine)
CAS No.	477243-03-1
Molecular Formula	C18H37NO2
Molecular Weight	299.49 g/mol
Synonyms	(2S,3R)-2-Amino-3-hydroxyoctadec-4-ene; Erythro-sphingosine; Sphing-4-enine; D-erythro-2-Amino-4-octadecene-1,3-diol; trans-4-Sphingenine; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol; Sphingosine (porcine brain); Long-chain base
EINECS	Contact for details

Quality Control

Our D-Erythro-Sphingosine (Brain, Porcine) is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support compliance with relevant GMP and ISO guidelines for laboratory reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic and moisture-sensitive; ensure the container is allowed to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: +4.0° to +6.0° (c=1 in CHCl3)
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.