Description

Palmitoyl 3-Carbacyclic Phosphatidic Acid is a synthetic, carbacyclic analog of a lysophosphatidic acid (LPA) derivative, representing a significant advancement in lipid signaling research. This compound is valued for its enhanced metabolic stability compared to its natural counterparts, making it a crucial tool for probing LPA receptor pharmacology and cellular signaling pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and advanced cosmetics sectors for drug discovery, target validation, and the development of novel bioactive ingredients.

Application

• Biomedical Research: A key pharmacological tool for studying lysophosphatidic acid (LPA) receptor subtypes (LPA1-6) in signal transduction, cell proliferation, and migration assays.
• Drug Discovery & Development: Serves as a stable reference compound or lead structure for developing novel therapeutics targeting LPA pathways in fibrosis, cancer, and neuropathic pain.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations targeting cellular repair, barrier function, and anti-aging mechanisms.
• Cell Culture & Biochemistry: Used as a defined lipid mediator in cell-based assays to study lipid metabolism, inflammation, and apoptosis.
• Diagnostic Development: Potential use as a standard or calibrant in developing analytical methods (e.g., LC-MS/MS) for detecting LPA analogs in biological samples.

Basic Information

Product Name	Palmitoyl 3-Carbacyclic Phosphatidic Acid
CAS No.	476310-22-2
Molecular Formula	C19H37O6P
Molecular Weight	392.47 g/mol
Synonyms	1-O-Palmitoyl-3-carbacyclic phosphatidic acid; 3-Carba-1-palmitoyl-sn-glycerol-2-phosphate; Carbacyclic LPA (C16:0); Cyclopropane-containing LPA analog; 2-(Hexadecanoyloxy)-3-(phosphonooxy)cyclopentane-1-carboxylic acid; Palmitoyl carbacyclic PA; cPA(16:0)
EINECS	Contact for details

Quality Control

Our Palmitoyl 3-Carbacyclic Phosphatidic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting research reproducibility and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, ethanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.