Description

1,2-Diphytanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is a high-purity, synthetic phospholipid derivative featuring branched phytanoyl chains, which confer exceptional stability against oxidation and hydrolysis. This chemical matters for researchers and formulators requiring robust, long-lasting lipid bilayers or vesicles that resist degradation under challenging conditions. It is primarily needed by the pharmaceutical, biotechnology, and advanced materials industries for applications in drug delivery systems, membrane protein research, and the creation of stable artificial cell models.

Application

• Liposome & Nanoparticle Formulation: A key component for creating highly stable, long-circulating liposomal drug carriers and lipid nanoparticles (LNPs) for mRNA delivery.
• Membrane Protein Studies: Used to solubilize and stabilize integral membrane proteins in native-like lipid environments for structural and functional analysis.
• Biomimetic Membrane Systems: Essential for constructing robust planar lipid bilayers and supported membranes for biosensor development and electrophysiology.
• Model Membrane Research: Provides oxidation-resistant lipid vesicles for studying membrane dynamics, phase behavior, and peptide-lipid interactions.
• Advanced Material Science: Serves as a building block for functionalized surfaces, coatings, and self-assembled nanostructures with tailored properties.
• Diagnostic Reagents: Incorporated into assay components and calibration standards where lipid stability is critical for consistent performance.

Basic Information

Product Name	1,2-Diphytanoyl-Sn-Glycero-3-Phosphate (Sodium Salt)
CAS No.	474967-75-4
Molecular Formula	C43H82NaO8P
Molecular Weight	781.07 g/mol
Synonyms	DPhyPG (Na salt); 1,2-Diphytanoyl-sn-glycero-3-phosphoric acid sodium salt; 3-sn-Phosphatidic acid, 1,2-diphytanoyl-, sodium salt; Diphytanoyl Phosphatidic Acid Sodium Salt; PA(16:0/16:0) (phytanoyl); Sodium 1,2-bis(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphate; 1,2-Di-O-phytanyl-sn-glycero-3-phosphate sodium salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and lipid composition. Certificates of Analysis (COA) detailing all critical quality attributes are available upon request. We adhere to a quality management system to ensure traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus)	≥ 98%
Solubility	Soluble in chloroform, methanol, ethanol; forms dispersions in aqueous buffers
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.