Description

1-o-Hexadecyl-2-Butenoyl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid analog, specifically a lysophosphatidylcholine derivative. This compound is of significant value in advanced research and development due to its role as a key intermediate and model compound for studying membrane biophysics, lipid signaling, and drug delivery systems. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers working on liposomal formulations, cell membrane mimics, and novel bioactive lipid conjugates.

Application

• Liposomal Drug Delivery: As a structural component for creating specialized liposomes with tailored surface properties and fusion characteristics.
• Biomembrane Research: Used as a model lipid to study membrane fluidity, phase behavior, and the incorporation of other lipid species in artificial bilayer systems.
• Cell Signaling Studies: Investigation of lysophosphatidylcholine (LPC) receptor interactions and downstream signaling pathways in physiological and pathological contexts.
• Pharmaceutical Intermediates: Serves as a critical synthetic building block for the production of more complex, target-specific phospholipid-based active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Functionalization point for attaching fluorescent tags, affinity labels, or other reporter molecules for diagnostic and imaging applications.
• Excipient Development: Evaluation as an innovative excipient to enhance the solubility, stability, or cellular uptake of poorly soluble drug candidates.

Basic Information

Product Name	1-o-Hexadecyl-2-Butenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	474944-25-7
Molecular Formula	C28H56NO7P
Molecular Weight	549.73 g/mol
Synonyms	1-Hexadecyl-2-butenoyl-sn-glycero-3-phosphocholine; 2-Butenoyl-LPC (C16:0); LysoPC(16:0/2:1); 1-Palmitoyl-2-butenoyl-sn-glycero-3-phosphocholine; (2R)-2-Butenoyl-1-hexadecyl-sn-glycero-3-phosphocholine; LPC(16:0/4:1(2E)); 1-O-Hexadecyl-2-(2-butenoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Butenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.