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n-Acetoyl-Ceramide-1-Phosphate (Ammonium Salt) CAS NO 474943-68-5


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CAS No.:474943-68-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Acetoyl-Ceramide-1-Phosphate (Ammonium Salt) is a high-purity, synthetic sphingolipid derivative, a critical intermediate in advanced lipid research and development. This compound is essential for studying and modulating key cellular signaling pathways, particularly those involving cell proliferation, differentiation, and apoptosis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries for developing novel therapeutics and high-performance bioactive formulations.

Application

  • Pharmaceutical R&D: As a key precursor or reference standard in the development of novel drugs targeting sphingolipid metabolism, such as potential anti-cancer or immunomodulatory agents.
  • Biochemical Research: For in vitro and in vivo studies to elucidate the role of ceramide-1-phosphate in cellular signaling, inflammation, and membrane biology.
  • Cosmeceutical Formulations: As a high-value active ingredient in premium skincare products aimed at enhancing skin barrier function, improving hydration, and providing anti-aging benefits.
  • Lipidomics & Analytical Standards: Serves as a critical analytical standard for mass spectrometry and chromatography in lipid profiling and quantitative analysis.
  • Cell Culture & Media Supplements: Used in specialized cell culture applications to study lipid-mediated effects on cell behavior and differentiation.

Basic Information

Product Name n-Acetoyl-Ceramide-1-Phosphate (Ammonium Salt)
CAS No. 474943-68-5
Molecular Formula C40H81N2O8P
Molecular Weight 749.06 g/mol
Synonyms N-Acetyl-Ceramide-1-Phosphate Ammonium Salt; N-Acetyl-D-erythro-sphingosine-1-phosphate ammonium salt; C2-Ceramide-1-Phosphate ammonium salt; N-Acetylsphingosine-1-phosphate ammonium salt; Ceramide 1-phosphate (N-acetyl, ammonium salt); N-Acetyl sphingosine 1-phosphate ammonium salt; (2S,3R,4E)-2-Acetamido-3-hydroxy-4-octadecen-1-yl dihydrogen phosphate ammonium salt
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Quality Control

Our n-Acetoyl-Ceramide-1-Phosphate (Ammonium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specification results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Solvent Residues (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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