Description

16:0-22:6 Pa is a highly purified phosphatidic acid (PA) species, a critical phospholipid signaling molecule. This specific molecular species, featuring palmitic acid (16:0) and docosahexaenoic acid (22:6) fatty acyl chains, is essential for advanced biochemical and pharmaceutical research. It is particularly valuable for researchers and manufacturers in the life sciences sector studying lipid-mediated cell signaling, membrane dynamics, and the development of lipid-based therapeutics.

Application

• Biochemical Research: A key reagent for studying phosphatidic acid's role as a lipid second messenger in cellular processes like membrane trafficking, cytoskeletal reorganization, and stress responses.
• Lipidomics & Analytical Standards: Used as a high-purity reference standard for the identification and quantification of phosphatidic acid species in complex biological samples via LC-MS/MS.
• Pharmaceutical Development: Serves as a critical component in the formulation of liposomal drug delivery systems and as a precursor for synthesizing other bioactive phospholipids.
• Cell Biology & Signaling Studies: Applied in in vitro and in vivo experiments to investigate the specific functions of DHA-containing phosphatidic acids in neurological and inflammatory pathways.
• Enzyme Substrate: Utilized as a specific substrate for assaying the activity of phospholipase D (PLD) and other lipid-modifying enzymes.
• Nutraceutical Research: Investigated for its potential bioactive properties stemming from its unique combination of saturated and long-chain polyunsaturated fatty acids.

Basic Information

Product Name	16:0-22:6 Pa
CAS No.	474943-28-7
Molecular Formula	C45H79O8P
Molecular Weight	779.08 g/mol
Synonyms	1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphate; PA(16:0/22:6); Phosphatidic Acid(16:0/22:6); 1-Hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate; DHA-Containing Phosphatidic Acid; 16:0/22:6 Phosphatidate; (16:0-22:6) PA
EINECS	Contact for details

Quality Control

Our 16:0-22:6 Pa is produced under stringent conditions to ensure the highest standards of purity and structural integrity, suitable for sensitive research applications. Each batch is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and fatty acid composition is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Fatty Acid Composition (GC)	16:0 ~45-50%, 22:6 ~45-50%
Solubility	Soluble in chloroform, methanol, ethanol; forms dispersions in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.