Description

1,2-Dioleoyl-Sn-Glycero-3-[n-(5-Amino-1-Carboxypentyl)Iminodiacetic Acid Succinyl] (Ammonium Salt) is a high-purity, functionalized phospholipid derivative designed for advanced research and formulation. This compound is critical for creating targeted drug delivery systems and diagnostic agents due to its unique chelating headgroup. It is primarily utilized by pharmaceutical researchers and manufacturers in the development of liposomal therapeutics, contrast agents, and other sophisticated nanomedicines.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key functional lipid for constructing targeted liposomes for drug and gene delivery.
• Diagnostic Imaging Agents: Serves as a chelating anchor for radionuclides (e.g., Technetium-99m, Gallium-68) in SPECT and PET imaging probes.
• Targeted Cancer Therapy: Enables surface functionalization of nanocarriers with targeting ligands for site-specific drug delivery.
• Magnetic Resonance Imaging (MRI) Contrast Agents: Used to conjugate gadolinium or other paramagnetic ions to lipid-based carriers.
• Bioconjugation and Surface Modification: Provides a reactive handle for attaching peptides, antibodies, or other biomolecules to lipid membranes.
• Research Grade Biochemicals: Essential reagent in academic and industrial labs studying membrane biophysics and targeted delivery mechanisms.

Basic Information

Item	Details
Product Name	1,2-Dioleoyl-Sn-Glycero-3-[n-(5-Amino-1-Carboxypentyl)Iminodiacetic Acid Succinyl] (Ammonium Salt)
CAS No.	474942-78-4
Molecular Formula	C52H96N3O12 • xNH3
Molecular Weight	Contact for details
Synonyms	DODAG; DODAG Succinyl; 1,2-Dioleoyl-sn-glycero-3-N-(5-amino-1-carboxypentyl)iminodiacetic acid succinyl ammonium salt; N-(5-Amino-1-carboxypentyl)iminodiacetic acid, 1,2-di-9-octadecenoyl-3-succinyl-sn-glycerol ester, ammonium salt; DOGS-NTA-Ni; Phospholipid-DTPA conjugate; NTA-DOGS; Chelating lipid for metal ions
EINECS	Contact for details

Quality Control

Our 1,2-Dioleoyl-Sn-Glycero-3-[n-(5-Amino-1-Carboxypentyl)Iminodiacetic Acid Succinyl] (Ammonium Salt) is manufactured under strict quality systems suitable for research and pharmaceutical development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and critical impurities. We ensure compliance with relevant ICH guidelines and can provide material for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95% (Area %)
Solvent Residue (GC)	Meets ICH limits
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.