Description

n-Lauroyl-D-Erythro-Sphinganylphosphorylcholine is a synthetic, high-purity sphingolipid analog, specifically a lauroylated derivative of sphingosylphosphorylcholine. This compound serves as a critical biochemical tool and a key intermediate in lipidomics research and the development of novel therapeutics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries for studying cell signaling pathways, membrane biophysics, and as a precursor for more complex bioactive lipids.

Application

• Biochemical Research: As a standard or substrate for studying sphingolipid metabolism, ceramide-related signaling pathways, and lipid second messengers.
• Pharmaceutical Development: A key intermediate in the synthesis of novel drug candidates targeting sphingolipid-mediated processes in oncology, immunology, and neurology.
• Lipidomics & Analytical Standards: Used as a high-purity reference standard in mass spectrometry (LC-MS/MS) for the identification and quantification of complex lipids in biological samples.
• Cosmeceutical R&D: Investigated for its potential bioactive properties in advanced skincare formulations aimed at modulating skin barrier function and cellular communication.
• Cell Culture & Media Supplements: Employed in specialized cell culture systems to study the effects of specific sphingolipids on cell growth, differentiation, and apoptosis.
• Enzyme Assay Substrate: Serves as a specific substrate for assays involving sphingolipid-metabolizing enzymes such as sphingomyelinases or ceramidases.

Basic Information

Product Name	n-Lauroyl-D-Erythro-Sphinganylphosphorylcholine
CAS No.	474923-31-4
Molecular Formula	C35H71N2O6P
Molecular Weight	646.93 g/mol
Synonyms	Lauroyl-Sphingosylphosphorylcholine; N-Lauroyl-D-erythro-sphingosylphosphorylcholine; SPC (Lauroyl); D-erythro-Sphingosine, 1-O-phosphocholine 2-N-lauroyl-; Lyso-N-lauroyl-sphingomyelin; Lauroyl-SM(d18:1); N-Lauroyl-sphingosylphosphocholine; Sphingosylphosphorylcholine Lauroyl Ester
EINECS	Contact for details

Quality Control

Our n-Lauroyl-D-Erythro-Sphinganylphosphorylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.