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D-Erythro-Sphinganine-1-Phosphate (C17 Base) CAS NO 474923-29-0


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CAS No.:474923-29-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Erythro-Sphinganine-1-Phosphate (C17 Base) is a high-purity, bioactive sphingolipid metabolite essential for cellular signaling research. This compound serves as a critical intermediate and analytical standard in the study of sphingolipid metabolism and its role in cell regulation, apoptosis, and disease pathways. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on lipidomics, metabolic disorders, and novel therapeutic target discovery.

Application

  • Biochemical Research: Used as a key intermediate and reference standard in sphingolipid metabolic pathway studies.
  • Pharmaceutical Development: Serves as a critical starting material or analytical standard for drug discovery programs targeting sphingosine kinase and related enzymes.
  • Cell Signaling Studies: Essential for investigating the role of sphinganine-1-phosphate in intracellular signaling, cell proliferation, and apoptosis.
  • Lipidomics Analysis: Employed as a high-purity calibrant and internal standard in mass spectrometry-based lipid profiling.
  • Enzyme Assays: Utilized as a substrate for studying the activity and inhibition of sphingosine kinases and other lipid-modifying enzymes.
  • Academic Research: Fundamental tool for universities and research institutes exploring the biochemistry of complex lipids and their physiological functions.

Basic Information

Product Name D-Erythro-Sphinganine-1-Phosphate (C17 Base)
CAS No. 474923-29-0
Molecular Formula C17H38NO5P
Molecular Weight 367.46 g/mol
Synonyms D-erythro-Sphinganine 1-Phosphate; D-erythro-Dihydrosphingosine 1-Phosphate; (2S,3R)-2-Amino-3-hydroxyoctadecyl dihydrogen phosphate; Sa1P; Dihydro-S1P; C17-Sphinganine-1-phosphate; D-erythro-C17-Sphinganine-1-P; D-erythro-C17-Dihydrosphingosine-1-phosphate
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Quality Control

Our D-Erythro-Sphinganine-1-Phosphate (C17 Base) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (MS) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0 %
Solubility Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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