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4-Nitrophenyl 2-(Acetylamino)-2-Deoxy-β-D-Glucopyranoside 6-(Hydrogen Sulfate) Monosodium Salt CAS NO 467446-91-9
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CAS No.:467446-91-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Nitrophenyl 2-(Acetylamino)-2-Deoxy-β-D-Glucopyranoside 6-(Hydrogen Sulfate) Monosodium Salt is a specialized chromogenic substrate designed for the sensitive detection and quantification of specific hydrolytic enzyme activities. This compound matters because it offers high specificity and a clear colorimetric readout, making it invaluable for precise biochemical research and diagnostic assay development. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical development, and clinical diagnostics sectors for studying enzymes like sulfatases and glycosidases.
Application
- Enzyme Activity Assays: As a chromogenic substrate for the kinetic study and high-throughput screening of sulfatase and glycosidase enzymes.
- Diagnostic Kit Development: A key reagent in the formulation of diagnostic kits for detecting enzyme deficiencies or pathological conditions.
- Biochemical Research: Used in fundamental research to investigate enzyme mechanisms, inhibition, and substrate specificity within metabolic pathways.
- Pharmaceutical R&D: Employed in drug discovery programs to identify and characterize potential enzyme inhibitors or activators.
- Quality Control in Biomanufacturing: Used to monitor and ensure the consistency and activity of enzyme preparations used in industrial processes.
Basic Information
| Product Name | 4-Nitrophenyl 2-(Acetylamino)-2-Deoxy-β-D-Glucopyranoside 6-(Hydrogen Sulfate) Monosodium Salt |
| CAS No. | 467446-91-9 |
| Molecular Formula | C14H17N2O11SNa |
| Molecular Weight | 428.35 g/mol |
| Synonyms | p-Nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranoside 6-sulfate sodium salt; 4-Nitrophenyl N-acetyl-β-D-glucosaminide 6-sulfate sodium salt; PNP-β-GlcNAc-6-SO4 Na; 4-Nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranoside-6-O-sulfate sodium salt; β-GlcNAc-6-S-PNP sodium salt; Chromogenic substrate for sulfatase; NAG6S-PNP sodium salt |
| EINECS | Contact for details |
Quality Control
Our 4-Nitrophenyl 2-(Acetylamino)-2-Deoxy-β-D-Glucopyranoside 6-(Hydrogen Sulfate) Monosodium Salt is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents | Meets ICH guidelines |
| Biological Activity | Functional in standard assay |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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