Description

4-Methylphenyl 1-Thio-α-D-Mannopyranoside is a specialized thioglycoside derivative of mannose, serving as a critical building block in synthetic carbohydrate chemistry. This compound matters for its role as a key glycosyl donor or acceptor in the stereoselective synthesis of complex oligosaccharides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of carbohydrate-based drugs, diagnostic tools, and biochemical probes. Its unique structure allows for precise manipulation in glycosylation reactions, making it invaluable for advancing glycobiology and therapeutic discovery.

Application

• Glycobiology Research: Used as a fundamental substrate for studying enzyme mechanisms, carbohydrate-protein interactions, and metabolic pathways.
• Pharmaceutical Synthesis: Serves as a key intermediate in the production of novel glycomimetics, antiviral agents, and cancer therapeutics.
• Diagnostic Reagent Development: Employed in the creation of labeled probes and assay components for detecting specific carbohydrates or enzymes.
• Enzymology Studies: Acts as a specific substrate or inhibitor for glycosidases and glycosyltransferases to elucidate their function.
• Chemical Biology Tool: Utilized for cell surface engineering, metabolic labeling, and the development of activity-based probes.
• Oligosaccharide Synthesis: A crucial glycosyl donor in automated or solution-phase synthesis of biologically active complex sugars.

Basic Information

Product Name	4-Methylphenyl 1-Thio-α-D-Mannopyranoside
CAS No.	457931-46-3
Molecular Formula	C13H18O5S
Molecular Weight	286.34 g/mol
Synonyms	p-Tolyl 1-Thio-α-D-mannopyranoside; 1-Thio-α-D-mannopyranoside 4-methylphenyl; α-D-Mannopyranoside, 1-thio-, 4-methylphenyl; p-Methylphenyl 1-thio-α-D-mannopyranoside; 4-Methylphenyl α-D-thiomannopyranoside; p-Tolyl α-D-thiomannoside; (2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-[(4-methylphenyl)thio]oxane-3,4,5-triol
EINECS	Contact for details

Quality Control

Our 4-Methylphenyl 1-Thio-α-D-Mannopyranoside is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.