Description

n-(Carboxymethyl)-n-[6-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Hexyl]-, Mono(4-Met CAS NO 445390-54-5 is a specialized functionalized maleimide derivative, engineered to serve as a high-performance linker or reactive intermediate in advanced synthesis. This compound is critical for creating stable, covalent bonds in polymer modification and bioconjugation applications, offering precise control over material properties. It is primarily sought by R&D and production teams in the pharmaceutical, advanced materials, and specialty polymer industries for developing targeted drug delivery systems, functional coatings, and cross-linked hydrogels.

Application

• Bioconjugation & Drug-Linker Synthesis: A key building block for attaching cytotoxic payloads, peptides, or fluorescent dyes to antibodies, proteins, or nanoparticles in ADC (Antibody-Drug Conjugate) and diagnostic probe development.
• Polymer Functionalization & Cross-linking: Used to introduce reactive maleimide groups into polymer backbones (e.g., PEG, polyacrylamides) for creating smart materials, hydrogels, and responsive coatings.
• Surface Modification: Enables the covalent immobilization of biomolecules or functional layers onto gold, silica, or polymer surfaces for biosensors and diagnostic devices.
• Peptide & Protein Modification: Facilitates site-specific labeling or cross-linking of thiol-containing biomolecules for structural studies and assay development.
• Advanced Material Research: Serves as a versatile intermediate in developing novel dendrimers, micelles, and other nanostructured delivery systems.
• Adhesive & Coating Formulations: Imparts enhanced adhesion and durability through covalent bonding mechanisms in high-performance industrial coatings.

Basic Information

Product Name	n-(Carboxymethyl)-n-[6-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Hexyl]-, Mono(4-Met
CAS No.	445390-54-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(6-((Carboxymethyl)amino)hexyl)-1H-pyrrole-2,5-dione; Maleimide-PEG6-acid; 6-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)amino)acetic acid; Maleimide-C6-Acid; Maleimide hexanoic acid derivative; N-(6-Maleimidocaproyl)glycine; Maleimide-PEG6-COOH; Acetic acid, 2-[[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)hexyl]amino]-
EINECS	Contact for details

Quality Control

Our production of this high-purity specialty chemical adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP and ISO 9001 standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant after each use to prevent degradation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.