Description

Hpd-Osu CAS NO 443305-32-6 is a high-purity, heterobifunctional crosslinking reagent widely used in advanced bioconjugation and chemical biology research. This compound is critical for creating stable, site-specific linkages between biomolecules, enabling the development of novel diagnostics and therapeutics. It is an essential tool for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require precise and reliable conjugation chemistry.

Application

• Antibody-Drug Conjugate (ADC) Development: A key reagent for linking cytotoxic payloads to monoclonal antibodies, forming stable ADCs for targeted cancer therapy.
• Protein-Protein and Protein-Peptide Conjugation: Facilitates the crosslinking of different biomolecules for studying protein interactions, signal transduction, and creating multi-functional protein complexes.
• Biomolecule Immobilization: Used to covalently attach proteins, antibodies, or enzymes to solid surfaces such as microarrays, biosensors, and chromatography resins.
• Fluorescent Probe and Label Synthesis: Enables the site-specific labeling of proteins and other biomolecules with fluorophores for imaging, detection, and diagnostic assays.
• Polymer-Biomolecule Hybrids: Employed in the synthesis of polymer-drug conjugates and smart biomaterials for controlled drug delivery systems.
• Diagnostic Reagent Manufacturing: Integral in the production of stable, high-affinity conjugates for immunoassays (ELISA, lateral flow tests) and other diagnostic platforms.

Basic Information

Product Name	Hpd-Osu
CAS No.	443305-32-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hpd-Osu; Hpd-OSu; 4-Hydroxyphenylpropionic acid N-hydroxysuccinimide ester; 3-(4-Hydroxyphenyl)propionic acid N-succinimidyl ester; 3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester; N-Succinimidyl 3-(4-hydroxyphenyl)propionate; N-Hydroxysuccinimide ester of 3-(4-hydroxyphenyl)propionic acid; HPPA-OSu
EINECS	Contact for details

Quality Control

Our Hpd-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the product label/COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.