Description

D-Erythro-Sphinganine-1-Phosphate (C20 Base) is a high-purity, biologically active sphingolipid metabolite, specifically the phosphorylated form of dihydrosphingosine. This compound serves as a critical intermediate and research tool in the study of sphingolipid signaling pathways, which regulate fundamental cellular processes. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors who are investigating cell proliferation, apoptosis, and metabolic disorders. The product is supplied with a guaranteed Certificate of Analysis to ensure reliability for sensitive applications.

Application

• Biochemical Research: A key standard and substrate for studying sphingolipid metabolism, enzyme kinetics (e.g., sphingosine kinases), and signaling cascades.
• Pharmaceutical Development: Used as a reference compound and intermediate in the discovery and development of novel therapeutics targeting cancer, inflammation, and metabolic diseases.
• Cell Biology Studies: Employed to investigate the role of sphinganine-1-phosphate in cell growth, differentiation, and programmed cell death (apoptosis).
• Metabolomics & Lipidomics: An essential analytical standard for the accurate identification and quantification of sphingolipid species in complex biological samples via LC-MS/MS.
• Enzyme Assay Development: Serves as a critical reagent for developing high-throughput screening assays for enzymes involved in the sphingolipid pathway.
• Academic Research: Fundamental tool for universities and research institutes exploring the biological functions of sphingolipids in health and disease models.

Basic Information

Product Name	D-Erythro-Sphinganine-1-Phosphate (C20 Base)
CAS No.	436846-91-2
Molecular Formula	C20H44NO5P
Molecular Weight	409.54 g/mol
Synonyms	D-erythro-Dihydrosphingosine 1-Phosphate; D-erythro-Sphinganine 1-Phosphate; (2S,3R)-2-Amino-3-hydroxyoctadecyl dihydrogen phosphate; Sa1P; Dihydro-S1P; D-erythro-C20-Sphinganine-1-P; C20 Dihydro-Sphingosine-1-Phosphate; D-erythro-Sphinganine phosphate
EINECS	Contact for details

Quality Control

Every batch of D-Erythro-Sphinganine-1-Phosphate (C20 Base) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identification data, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.