Description

S-3-3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Bi-2-Naphthol is a high-purity, chiral binaphthol derivative of significant importance in asymmetric synthesis. Its value lies in its role as a privileged ligand and catalyst precursor for a wide range of enantioselective transformations, enabling the production of optically active intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand for transition metal-catalyzed asymmetric reactions, including hydrogenation, coupling, and cycloaddition.
• As a precursor for constructing chiral organocatalysts used in enantioselective C-C bond formation.
• In the synthesis of advanced pharmaceutical intermediates where high enantiomeric purity is critical.
• For the development of novel materials with chiral properties, such as liquid crystals or polymers.
• In academic and industrial R&D for method development in asymmetric catalysis.
• As a resolving agent or chiral auxiliary in the purification and synthesis of enantiomerically pure compounds.

Basic Information

Product Name	S-3-3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Bi-2-Naphthol
CAS No.	435327-17-6
Molecular Formula	C40H32O2
Molecular Weight	544.68 g/mol
Synonyms	(S)-3,3'-Bis(3,5-dimethylphenyl)-1,1'-bi-2-naphthol; (S)-3,3'-Di(3,5-xylyl)-BINOL; S-3,3'-Bis(3,5-dimethylphenyl)-BINOL; (S)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol; (S)-3,3'-Dixylyl-BINOL; S-DM-BINOL; S-3,3'-Ar2-BINOL (where Ar = 3,5-dimethylphenyl); Chiral Binaphthol Derivative
EINECS	Contact for details

Quality Control

Our S-3-3'-Bis(3,5-Bis(Methyl)Phenyl)-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.