Description

Rink Amide MBHA Resin is a specialized, high-quality solid-phase synthesis support designed for the efficient production of peptides, particularly those with C-terminal amides. Its robust chemical stability under strong acid conditions makes it an indispensable tool for researchers and manufacturers requiring reliable and high-loading capacity. This resin is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the synthesis of peptide-based drug candidates, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): The primary application for the synthesis of peptides, especially those requiring a C-terminal carboxamide group.
• Combinatorial Chemistry: Used in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Peptide Drug Manufacturing: A critical raw material in the scalable production of therapeutic peptides and peptide hormones.
• Bioconjugation & Labeling: Serves as a solid support for attaching peptides to other molecules, such as fluorophores or proteins, for diagnostic and research applications.
• Academic & Industrial Research: Essential for fundamental studies in peptide chemistry, structure-activity relationships (SAR), and new synthetic methodology development.

Basic Information

Product Name	Rink Amide MBHA Resin
CAS No.	431041-83-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid MBHA resin; Rink Amide AM Resin; Rink Amide Linker MBHA Resin; MBHA Rink Amide Resin; Fmoc-Rink Amide MBHA Resin; Peptide Synthesis Resin; Rink Amide Solid Support; 4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxyacetamido-methylbenzylhydrylamine Resin
EINECS	Contact for details

Quality Control

Our Rink Amide MBHA Resin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including determination of loading capacity, functional group integrity, and purity assessment to ensure consistent performance in peptide synthesis. Certificates of Analysis (COA) with detailed specifications are available for every lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The resin is stable in strong acid/organic solvent environments typical for SPPS but should be kept under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal reactivity and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white beads
Loading Capacity	0.4 - 0.8 mmol/g (typical)
Particle Size	100-200 mesh
Identification (IR)	Conforms to structure
Moisture Content (KF)	< 5%
Functional Test	Pass

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.