Description

6-Chloro-3-Indoxyl-α-D-Mannopyranoside is a specialized chromogenic substrate used in enzymatic detection and diagnostic assays. Its core value lies in its ability to produce a distinct, insoluble blue precipitate upon cleavage by specific glycosidase enzymes, enabling precise visualization and quantification. This compound is essential for researchers and manufacturers in the life sciences, particularly for applications in microbiology, cell biology, and the development of diagnostic kits.

Application

• Microbiological Media: Selective detection and differentiation of bacterial colonies expressing α-mannosidase or related enzymes.
• Diagnostic Assays: Key substrate in clinical and research ELISA, blotting, and histochemical staining procedures for enzyme activity.
• Cell Biology Research: Used as a reporter substrate to study glycosidase activity and gene expression in eukaryotic cells.
• Enzyme Characterization: Employed in biochemical studies to determine the kinetics and specificity of α-glycosidases.
• Quality Control Testing: Utilized in pharmaceutical and biotech manufacturing for monitoring microbial contamination or specific enzymatic processes.

Basic Information

Product Name	6-Chloro-3-Indoxyl-α-D-Mannopyranoside
CAS No.	425427-88-9
Molecular Formula	C14H16ClNO7
Molecular Weight	345.73 g/mol
Synonyms	6-Chloro-3-indolyl-α-D-mannopyranoside; 6-Cl-3-Indoxyl-α-D-mannoside; 6-Chloro-3-indoxyl α-D-mannoside; 5-Chloro-3-indolyl α-D-mannopyranoside; 6-Chloro-3-indolyl α-D-mannopyranoside; α-D-Mannopyranoside, 6-chloro-3-indolyl; Chromogenic substrate for α-mannosidase; 6-Cl-α-Man
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Indoxyl-α-D-Mannopyranoside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or manufacturing grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.