Description

Rac-Anabasamine CAS NO 400738-05-8 is a synthetic alkaloid derivative of significant interest in advanced chemical research and development. This compound serves as a crucial chiral building block and reference standard for the synthesis and study of nicotinic acetylcholine receptor (nAChR) ligands. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and academic research institutions focused on neuroscience, medicinal chemistry, and plant protection science.

Application

• Pharmaceutical Research Intermediate: A key chiral precursor in the synthesis of novel nAChR-targeting drug candidates for neurological and cognitive disorders.
• Reference Standard for Analytical Chemistry: Used as a high-purity standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Agrochemical Development: Investigated as a lead structure or intermediate for developing new classes of plant-derived insecticides and nematicides.
• Neuroscience & Pharmacology Studies: Employed in *in vitro* and *in vivo* studies to understand the structure-activity relationships (SAR) of anabasine-related alkaloids.
• Chemical Biology Probe: Utilized as a tool compound to probe the function and distribution of specific nAChR subtypes in biological systems.
• Process Chemistry & Scale-Up: Serves as a model compound for developing and optimizing asymmetric synthesis and chiral separation processes.

Basic Information

Product Name	Rac-Anabasamine
CAS No.	400738-05-8
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(±)-Anabasamine; DL-Anabasamine; rac-2-(3-Pyridyl)piperidine; 2-(Pyridin-3-yl)piperidine (racemic); 3-(2-Piperidyl)pyridine; Anabasamine Racemate; (±)-2-(3-Pyridinyl)piperidine; DL-2-(3-Pyridyl)piperidine
EINECS	Contact for details

Quality Control

Our Rac-Anabasamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral composition is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC, Area %)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Racemic mixture (50:50 enantiomeric ratio)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.